For those who are an offline player one tip is to NBA 2K22 MT use the new features Visual Concepts made to AI help defend. In the past, defensive players would come at you from an axe and leave their man in the air. This made it easier to hunt three on the wings if you were struggling to score.
In 2K22, those defenders don't seem to crash as often and you can play a a pick-and-roll game that feels more authentically like an NBA game. The game is now about being aware of the defense and making the right decision. If you request your center to make a choice and the player is able to switch to you, give it over to the big guy and let him battle smaller defenders. If they don't switch congratulations on having a clear lane. Get to the bucket and make a layup, or be fouled.
To begin a Pick-and-Roll, press and hold L1 (LB to play on Xbox) with your finger pointed toward whichever player you want to select. It is important to be patient. If you are unable to find the switch but don't see an available lane, you shouldn't force it. Reset and try again. Remember, you're trying to play it smart and slowly.
This is the case for players who are looking to dive into the NBA 2K22 game this year. You can choose to play MyTeam, MyCareer, or MyWNBA, you probably need to make a choice and stick to the game. But that doesn't mean you can't play around with other modes, however all three have a season pass that includes content to unlock. It seems a bit easier to Cheap 2K22 MT finish out the pass than in the past, but in the event that you're spread too much, you may not receive all of the rewards.